How ETH Zürich Became a Startup Machine: Frank Floessel & Vanessa Wood (#549)
March 12, 2026
Co-produced by
Co-produced by
7:59 - ETHs Modernization in Supporting for Founders and Startups
21:03 - Growth of Spin-offs and Startups at ETH
29:52 Identifying Gaps in the Ecosystem
35:43 Metrics for a Healthy Ecossystem
Episode Description:
In this episode we’re joined by Vanessa Wood, Vice President for Knowledge Transfer and Corporate Relations at ETH Zurich, and Frank Floessel, Head of ETH Entrepreneurship. Vanessa oversees how ETH connects its research with industry, government, and society, such as partnerships, intellectual property, and spin-offs. Frank brings the perspective of a founder and operator: after studying electrical engineering at ETH, he co-founded Tempobrain before returning to help shape the next generation of entrepreneurs at ETH.
In the conversation, we explore how ETH is transforming its approach to entrepreneurship, making the spin-off process faster, clearer, and more founder-friendly. They also go into why deep tech could be Europe’s opportunity to compete globally again, with institutions like ETH producing the research and talent needed to build the next generation of companies. They then discuss the structural challenges still facing Europe - including the lack of late-stage liquidity and strong public markets compared to the U.S.
We also dive into the founder mindset behind successful startups. Vanessa explains why great technology alone doesn’t build a great company - founders also need to understand customers, markets, and how to assemble teams that can turn research into real products. Frank shares his own journey from ETH student to founder and back to the university, highlighting how successful entrepreneurs often return to support the next generation. Together, they discuss how ecosystems like ETH grow stronger over time as experienced founders reinvest their knowledge, networks, and capital into future startups
The cover portrait was edited by www.smartportrait.io.
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